Dimethyl Acetamide (DMAC)

Dimethyl Acetamide (DMAC), also known as N,N-Dimethylacetamide, is a clear, colorless liquid with an ammonia-like odor. It is a versatile solvent widely used in pharmaceutical manufacturing, polymer processing, and organic synthesis due to its high polarity and thermal stability.

CAS No: 127-19-5

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Formula

C₄H₉NO

Main Uses

Laboratory Chemicals

Appearance

Colorless liquid

Handling

Combustible – Handle with care

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Safety Highlights

DMAC is classified as a hazardous chemical due to its potential to harm reproductive health and its ability to cause eye irritation and acute toxicity. Proper handling and personal protection are essential.

Flammable Liquid

Flash point at 70°C. Keep away from heat, sparks, open flames, and hot surfaces.

Toxic on Contact

Harmful if inhaled or absorbed through the skin. May cause fatigue, dizziness, nausea, or respiratory irritation.

Corrosive Agent

Causes serious eye irritation. May damage the unborn child. Use only in controlled, ventilated environments.

Emergency Measures

In case of fire, use CO₂, dry chemical, or foam. For exposure, rinse thoroughly and seek medical attention immediately. Avoid inducing vomiting if ingested.

Proper Storage

Store in a tightly sealed container in a cool, dry, well-ventilated area under an inert atmosphere (e.g., nitrogen). Keep away from oxidizers and moisture.

Regulatory ID

UN No (Bulk): NA1993 (Combustible liquid, n.o.s.) | DOT Hazard Class: Combustible (Bulk) | Packaging Group: III

Environmental Care

DMAC is water-soluble and mobile in soil but not persistent. Do not allow to enter drains or aquatic environments.

PPE Required

Use nitrile or butyl gloves, chemical safety goggles, lab coat, and A-type respirator for organic vapors. Ensure eyewash and safety shower are accessible.

Frequently Asked Questions

Explore key information about Dimethyl Acetamide (DMAC), including its primary uses, health and environmental hazards, safe storage guidelines, and emergency protocols. These FAQs support safe handling and regulatory compliance for lab and industrial users.

What is Dimethyl Acetamide (DMAC) used for?

DMAC is used as a solvent in pharmaceuticals, resins, polymer production, and chemical research due to its high solvating power.

Is DMAC dangerous to human health?

Yes. It is harmful if inhaled or absorbed through the skin, may irritate the eyes, and can cause developmental toxicity. Handle with extreme caution.

How should DMAC be stored?

Store in a cool, dry, ventilated area in tightly sealed containers. Use an inert atmosphere like nitrogen and keep away from heat or oxidizers.

What should I do in case of a DMAC spill or exposure?

Evacuate the area. Wear PPE and use absorbent material to clean up. Avoid direct contact. Seek immediate medical help if exposed.

Is DMAC harmful to the environment?

DMAC is biodegradable but mobile in water systems. Avoid release into drains and dispose of in compliance with hazardous waste regulations.

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