Dibasic Calcium Phosphate, Dihydrate, Powder, USP

White, odorless powder used primarily as a pharmaceutical excipient (tablet diluent), dietary calcium source, and in veterinary/feed applications. While not flammable, it is classified under GHS/OSHA as causing skin and serious eye irritation and may cause respiratory irritation if inhaled as dust.

CAS No: 7789-77-7

Formula

CaHPO₄·2H₂O

Main Uses

Pharmaceutical tablet excipient/diluent, calcium supplement source

Appearance

White powder (solid), odorless.

Handling

Handle in well-ventilated areas.

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Safety Highlights

Classified as hazardous under OSHA/Hazard Communication Standard. Causes skin irritation, serious eye irritation, and may cause respiratory irritation on inhalation. Not combustible. Dust control is essential to prevent inhalation and dispersal.

Flammable Liquid

Causes irritation; prolonged contact may dry or chap skin. Wash promptly after exposure.

Toxic on Contact

Causes serious eye irritation; flush immediately on contact.

Corrosive Agent

Inhalation of dust can irritate the respiratory tract; avoid breathing dust.

Emergency Measures

Flush with water for at least 15 minutes; seek medical attention if irritation persists.

Proper Storage

Store tightly closed in a dry, well-ventilated area at room temperature. Protect from moisture and incompatible materials (oxidizing agents).

Regulatory ID

Not regulated for transport (not classified as dangerous for DOT/TDG/IMDG/IATA per provided SDS).

Environmental Care

Prevent material from entering drains, waterways, or confined spaces. Contain and clean spills; avoid spread.

PPE Required

Safety glasses with side shields or goggles, chemical-resistant apron/long-sleeved clothing, gloves, and dust respirator when airborne concentrations are elevated.

Frequently Asked Questions

Dibasic Calcium Phosphate Dihydrate can cause skin, eye, and respiratory irritation when dust is present, though it is not flammable or carcinogenic. This section outlines safe storage conditions, PPE requirements, emergency measures for accidental exposure, spill management, and environmental precautions.

Is Dibasic Calcium Phosphate Dihydrate considered hazardous?

It is classified as causing skin and serious eye irritation and may irritate the respiratory system if inhaled as dust. It is not flammable or carcinogenic, but precautions are needed to limit dust exposure.

How should this powder be stored?

Store in a tightly closed container in a dry, well-ventilated area at room temperature. Protect from moisture (it’s deliquescent) and keep away from oxidizing agents.

What personal protective equipment is needed during handling?

Use safety glasses or goggles, chemical-resistant gloves, protective clothing, and a dust respirator if ventilation is insufficient or dust is present. Follow proper hygiene and decontamination practices.

What actions should be taken in case of accidental exposure?

For eye contact, flush with water for 15 minutes and seek medical help if irritation continues. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air. If ingested, do not induce vomiting and consult a physician.

How should spills be managed and is it environmentally hazardous?

Prevent dust spread—cover spill, sweep or use appropriate tools to collect into disposal containers. Do not allow entry into drains or waterways. Dispose of per local regulations; significant uncontained releases should be contained and reported if required.

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