Chloroform

Chloroform (also known as trichloromethane) is a clear, sweet-smelling liquid commonly used as a solvent in laboratories and chemical manufacturing. It poses serious health hazards and must be handled with strict safety precautions.

CAS No: 67-66-3

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Formula

CHCl₃

Main Uses

Laboratory, Pharma

Appearance

Colorless, Volatile Liquid

Handling

Toxic – Use Extreme Caution

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Safety Highlights

Chloroform is classified as a toxic, carcinogenic, and reproductive hazard. It poses severe health risks through inhalation, ingestion, and prolonged exposure. Adequate ventilation, PPE, and secure storage are essential to safe use.

Flammable Liquid

Toxic if inhaled (H331). May cause drowsiness, dizziness, and CNS depression. Use in fume hood only.

Toxic on Contact

Suspected of causing cancer (H351) and damaging the unborn child (H361d). Avoid all unnecessary exposure.

Corrosive Agent

Causes liver and kidney damage through prolonged or repeated exposure if swallowed (H372). Use with long-term health monitoring.

Emergency Measures

Causes serious eye irritation and skin irritation (H319, H315). Immediate rinsing and decontamination required on contact.

Proper Storage

In case of inhalation, move to fresh air and seek immediate medical help. If ingested, do not induce vomiting—seek medical attention.

Regulatory ID

Store tightly sealed in a well-ventilated, locked area accessible only to trained personnel. Keep away from light, heat, and incompatible materials.

Environmental Care

UN No: 1888 | DOT Hazard Class: 6.1 (Toxic) | Packaging Group: III

PPE Required

Viton® gloves for full contact, Butyl rubber gloves for splash contact

Frequently Asked Questions

Find essential answers to common questions about Chloroform, including its applications, health risks, safe storage, and emergency handling procedures. This section helps promote informed use and compliance with lab safety standards.

What is chloroform used for?

Chloroform is primarily used as a laboratory solvent and in chemical synthesis. It is also historically known for use in anesthetics and extraction processes.

Is chloroform dangerous to inhale?

Yes. It is toxic when inhaled and can affect the central nervous system, causing dizziness, nausea, or unconsciousness. Always use in a fume hood.

Does chloroform cause long-term health effects?

Yes. Repeated exposure can damage the liver and kidneys and is suspected to cause cancer and reproductive harm. Long-term monitoring is recommended.

How should chloroform be stored safely?

Keep it tightly closed in a cool, dark, and ventilated area. Store away from incompatible materials like strong bases, oxidizers, and metals.

What should I do in case of a chloroform spill or exposure?

Evacuate the area, wear appropriate PPE, and absorb the spill using liquid-absorbent material. Seek medical help immediately if exposure occurs.

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